Ovarian Cancer Trends In São Paulo, Brazil: 1997-2011

Larissa LORIATO, School of Public Health, University of São Paulo, Brazil

1 Department of Epidemiology, School of Public Health, University of São Paulo
2 Population-based Cancer Registry of São Paulo, Department of Epidemiology, School of Public Health, University of São Paulo

Ovarian cancer trends in São Paulo, Brazil: 1997-2011.
Purpose: The ovarian cancer (OC) behaves differently around the world, with the highest incidence rates occurring in populations of Central and Eastern Europe. The aim of the study was to describe OC patterns in the Municipality of São Paulo, Brazil, from 1997 to 2011.
Methods: Incident cases (C56, ICD-10) were provided by the São Paulo Population-based Cancer Registry. Deaths (C56, ICD-10) were obtained from the DATASUS online platform. Crude and Age-standardized (SEGI´s world population) for incidence and mortality rates per 100,000/women were calculated. Incidence tumors were classified as serous carcinoma, mucinous carcinoma, endometrioid carcinoma and adenocarcinoma. Age was grouped into the following age groups:< 35, 35-49, 50-59, 60-69, 70-79, and 80+. The coefficients were calculated by age and histological group. Trend analysis was conducted using the Joinpoint software, by estimating the Annual Percent Change (APC). Statistical analyses were considered as significant when p values < 0.05.
Results: 7,882 cases were diagnosed and 3,924 deaths were recorded from OC. Both incidence and mortality showed decreasing trends having APC -6.6% and -1.2%, respectively. The most significant declines in incidence and mortality were seen among women aged 50 and older. In the mortality trend is decreasing only from 50 to 79 years old and the other age groups remained stable. All histological groups had decreasing trends, except adenocarcinoma remained stable.
Conclusions: This study concluded that, overall, the trend of incidence and mortality in São Paulo is decreasing, and the trend of incidence had a greater decrease.
Funding source: Support Foundation of São Paulo Research