Head And Neck Cancer Trends Using A Single Hospital-Based Cancer Registry, São Paulo, Brazil, 2008-2012

Rossana MENDOZA LOPEZ, Instituto do Câncer do Estado de São Paulo, Brazil
LOPES E. 2 , CAMPOLINA A. 1 , HOFF P. 3 , CHAMMAS R. 3

1 Centro de Investigação Translacional em Oncologia, Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil
2 Registro Hospitalar de Câncer, Instituto do Câncer do Estado de São Paulo, São Paulo, Brazil
3 Departamento de Radiologia e Oncologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil

Purpose: To describe epidemiological trends of patients with head and neck cancer, using a hospital-based cancer registry (HBCR).
Methods: This was a HBCR study carried out at a reference hospital for cancer treatment in Sao Paulo, Brazil, between 2008-2012. Records were retrieved and data about patients with head and neck cancer (oral cavity, oropharynx, hypopharynx, larynx, and not specified types), over 18 years, were included in the analysis. The calculation of relative risk (RR) was performed by Poisson regression with 95% confidence intervals. Analyses were performed using SPSS for Windows v.18.
Results: 1801 cases of head and neck cancer were diagnosed in the period, most of them were men (1,509 cases, 83.8%), mean age was 59 years (standerd deviation [SD] = 10.7 years). Among men, the most common tumors were located in the oropharynx (34.2%), followed by laryngeal tumors (9.5%). Among women, both the oropharynx and the larynx tumors had the same frequency (27.4%). More than 95% of the tumors were squamous cell carcinomas. A growing trend for all tumors frequencies was observed: oral cavity (RR = 1.18, 95% CI 1:09 to 1:27), oropharynx (RR = 1.23, 95% CI 1:16 to 1:31), hypopharynx (RR = 1.17, 95CI% 1:05 to 1:30) and larynx (RR = 1.20, 95% CI 1:12 to 1:27).
Conclusions: The analysis allowed us to observe a growing frequency trend in head and neck cancer at a reference center, over the last years. These findings should motivate further epidemiological investigations of differential associations of environmental factors, such as tobacco, alcohol and human papillomavirus infection.
Funding source: No funding.