Trends In Incidence And Mortality Of Esophagus Cancer In The Municipality Of São Paulo, São Paulo, Brazil, 1997-2012

LATORRE M. ^1,2 , TANAKA L. ^1,2 , OLIVEIRA M. ¹ , ABREU L. ¹ , SANTOS A. ¹

Introduction: Esophageal cancer, although infrequent, it is an extremely lethal disease, which frequently affects men over 50s. This study aimed to verify the trends of incidence and mortality from esophageal cancer in São Paulo. Methods: The incident cases of esophageal cancer (C15, ICD-10) 1997-2012 were obtained from the population-based cancer registry of São Paulo. Deaths were obtained in DATASUS for the same period (1997-2012). The crude incidence and mortality rates were calculated based on population provided by the IBGE and adjusted considering the world population of Segi. The trend analyzes were performed for incidence and mortality by sex and age group (30-39, 40-49, 50-59, 60-69, 70 and over) using the Joinpoint software. The results were presented as annual percent change (APC). Results: Some 9219 cases were newly diagnosed (78.15% in men) and 6,513 deaths (81.04% men) occurred during the period. There was a significant decrease in incidence for males and females of -4.2% and -1.4%, respectively. This decreasing pattern was found for all age groups, except for the 30 to 39 age group, which was stable, for men and women, being more pronounced among men. For mortality, a similar pattern was found for both men and women: -1.5% and -3.1%, respectively. Among the youngest age groups (<60s), for females, the mortality rate has been stable, and a decrease in the age group 60-69 years (-3, 2%) and aged 70 or older (-1.4%). For males, the mortality rate has been stable for the age group 50-59 years and decreasing trends were found for the remaining age groups: 30-39 years (-9.3%), 40-49 years (-2.7%), 60-69 years (-2.2%) and 70 and over (-1.4%). Conclusion: The observed trends reflect changes in the behavior of the population regarding lifestyle, for example, tobacco consumption.