Monitoring Oral, Oropharyngeal And Larynx Cancer Survival In A Tertiary Cancer Center ñ ACCamargo Cancer Center (ACCC) São Paulo, Brazil

Maria CURADO, ACCAMARGO CANCER CENTER , Brazil
RODRIGUES MENDONÇA E SILVA D. 1 , DAMASCENA A. 2 , KOWALSKI L. 2 , IKEDA M. 2 , TORLONI H. 3

1 Department of Epidemiology and Statistics, International Research Center, Accamar Cancer Center, São Paulo, Brazil
2 Department of Head and Neck Surgery and Otorhinolaryngology, ACCamargo Cancer Center, São Paulo, Brazil
3 Hospital Cancer Registry, ACCamargo Cancer Center, São Paulo, Brazil

Introduction: Analyse survival rates from specialized cancer centers is an important activity to measures treatment outcomes, in cancer patients. Oral, Oropharyngeal and larynx cancer are a malignancies in which a multidisciplinary therapeutic approach is mandatory. Although there was improvement for cancer care survival rates remain almost unchanged for these malignancies.
Purpose: To describe survival rates in two periods from 2000 to 2010 at ACCCC/Brazil,  and  to verify mortality  trends in  the city of  Sao Paulo  1998 to 2012.
Methods: Data was stratified in two periods 2000-2004 and 2005-2010 .Variables analysed were gender, age, clinical stage, treatment specific and overall survival. Mortality data was abstracted from datasus.
Results:  Oral Tongue was the most common site (42%) followed by Floor of mouth (18%). Stage I and II proportion increased from 26%, 2000 to 2004 to 37% in the period 2005 to 2010 (p<0.001). Five years cancer specific survival rates was 61% in 2000 to 2004 and 59% 2005-2010 (p 0.659).
Oropharynx Tonsil was the most common site (34%) followed by base of tongue (30%). Early stage (I e II) decrease 1% from 11%, 2000 to 2004; to 10% from 2005 to 2010. Five years cancer specific survival was 52% 2000 to 2004 and 66% (p 0,004) 2005-2010.
Larynx Glotis was the most common site (53%) followed by supraglotis (20%). Early stage proportion (I and II) increased from 39% ( 2000 - 2004) to 41% in 2005 to 2010. Cancer specific survival at 5 years was 73% 2000 to 2004 and 75% 2005-2010 (p 0,523).  
Mortality trends remained almost unchanged in the population of Sao Paulo.
Conclusion: Survival of oral and larynx, remain unchanged, while for oropharyngealincreased; mortality rates remains stable in Sao Paulo.