Incidence Of Childhood Cancer In Slovakia: Results For Period 2000-2012

Miroslava MAKOHUSOVA, Bratislava, Slovakia, Slovakia
KAISEROVA E. 1 , COLOMBET M. 2 , BUBANSKA E. 3 , ORAVKINOVA I. 4 , STANCOKOVA T. 3 , PUSKACOVA J. 1 , KOLENOVA A. 1 , STELIAROVA-FOUCHER E. 2

1 Department of Pediatric Hematology and Oncology, Comenius University and University Children ́s Hospital Bratislava, Bratislava, Slovakia
2 Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France
3 Department of Pediatric Oncology and Hematology, Children’s University Hospital, Slovak Medical University, Banska Bystrica, Slovakia
4 Department of Pediatric Hematology and Oncology, University Children ́s Hospital, Pavol Jozef Safarik University, Kosice, Slovakia
5 Department of Chemistry, Faculty of Natural Sciences, University of SS. Cyril and Methodius, Trnava, Slovakia

Purpose: The aim of the study was to describe cancer incidence in children (age-range 0-14 years) registered by National Slovak clinical cancer registry of children and adolescents for the period 2000-2012.
Methods: Patients were identified in three regional pediatric treatment centers (Bratislava, Banska Bystrica and Kosice), which use the same treatment strategies. The registry includes all tumors, irrespective of behavior, and includes skin tumors and histiocytosis X. During internship in IARC in 2014-2015, all cancer cases have been recoded from the original ICD-10 classification to the ICD-O-3 and ICCC-3 classifications, uploaded to tailored Can-Reg 5 software and analysed for incidence rates.
Results: In 2000-2012, 1,630 cases were registered in the registry. Among them, 95.6% were confirmed microscopically. The age-standardized (World standard) annual incidence rate (ASR) was 145.1 per million person-years. The most frequent were leukaemias (ASR=44.5), followed by CNS tumours (ASR=31.7) and lymphomas (ASR=15.4). The recorded data showed an average annual increase of 1.72% (p=0.01). 
Conclusions: The observed incidence rates are comparable with those reported from National cancer registry of Slovakia (NOR) and also neighbouring countries. It is important to ensure long-term monitoring and put in place a mechanism of data exchange with the NOR, to improve data quality and completeness in both sources.
Funding source: National Scholarship Program of the Slovak Republic (NSP), IARC stipendium