The National Cancer Institute (NCI) Cohort Consortium

Chinonye (Nonye) HARVEY, National Cancer Institute, United States

1 Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland, USA

An epidemiologic consortium is a group of scientists from multiple institutions who have agreed to cooperative research efforts involving, but not limited to, pooling of information from multiple population studies for the purpose of combined analyses, and is able to address scientific questions that cannot otherwise be addressed through the effort of investigators at a single institution.  The National Cancer Institute (NCI) sees consortia as providing unique opportunities for advancing cancer epidemiology by virtue of the large sample size of study participants and the synergy resulting from the interdisciplinary expertise of the membership.  First convened in 2000, the Cohort Consortium (CoCo) is one of the largest research consortia supported by the NCI; comprised of 57 U.S. and international cohorts, totaling over 7 million study participants.  The purpose of CoCo is to serve as a research resource providing data and biospecimens to study gene-gene and gene-environment interactions in the etiology of cancer. The major initiatives are:  1) Breast and Prostate Cancer Cohort Consortium (BPC3). 2) Pancreatic Cancer Cohort Consortium. 3) African American BMI Working Group. 4) BMI and All Cause Mortality Pooling Project. 5) Diabetes and Cancer Initiative in the Cohort Consortium. 6) Lung Cancer Cohort Consortium. 7) Tumor Tissue Working Group. 8) Rare Cancers Vitamin D Pooling Project.
Basic demographic information and findings on these studies of the CoCo will be presented and information on how to participate in these initiatives.  These important scientific findings would not have been possible without the formation of a large scale research collaboration, like the CoCo. Collaboration in the consortium enables investigators to share data and resources, expand study populations and create opportunities to pursue unique research studies.  The CoCo is open to new research proposals and researchers are encouraged to contact the project principal investigators.